AKTIVITAS FARMAKOLOGI DAN KADAR SENYAWA FENOLIK TOTAL DARI TANAMAN ANDONG MERAH (Cordyline fruticosa L. A. Chev.)
Keywords:
Cordyline fruticosa, Frmakologi, Fenolik totalAbstract
Tanaman andong merah (Cordyline fruticosa L. A. Chev) merupakan jenis tanaman hias yang banyak digunakan sebagai pengobatan tradisional di berbagai negara. Metabolit sekunder yang terkandung dalam tanaman andong merah antara lain polifenol, flavonoid, saponin, alkaloid, steroid dan triterpenoid. Studi literatur ini bertujuan mengkaji artikel yang diperoleh untuk memberikan informasi terkait aktivitas farmakologi dan kandungan senyawa fenolik total dari tanaman andong merah. Metode yang digunakan yaitu penelusuran artikel nasional maupun internasional dengan bantuan Google Scholar. Kata kunci yang digunakan yaitu “Cordyline fruticosa L. A. Chev atau Cordyline terminalis Kunth”. Kriteria inklusi yang digunakan yaitu literatur primer yang dipublikasi pada tahun 2011-2020 yang membahas tentang aktivitas farmakologi dan kadar senyawa fenolik total dari tanaman andong merah. Kriteria eksklusi yang digunakan adalah artikel yang membahas tentang aktivitas farmakologi dan kadar senyawa fenolik total dari tanaman andong merah yang dipublikasi sebelum tahun 2011 dan tidak bisa diakses secara full text. Analisis 11 jurnal hasil penelitian pada studi literatur ini menunjukkan bahwa tanaman andong merah berpotensi dikembangkan sebagai agen antioksidan, antidiabetes, antidiare, antibakteri, sitotoksik, hemostatik, antimalaria, analgesic, antiinflamasi dan antipiretik. Ekstrak metanol dari daun tanaman andong merah memiliki kadar senyawa fenolik total sebesar 106,2 mg/g GAE.
References
Adaku C., Skaar I., Byamukama R., Jordheim M.
and Andersen Ø.M., Anthocyanin Profile and
Antioxidant Property of Anti-asthma Flowers
of Cordyline terminalis (L.) Kunth
(Agavaceae), Natural Product
Communications; 2020; 15 (5), 1–7.
Ahmad A.R., Juwita J. and Ratulangi S.A.D., 2015,
Penetapan Kadar Fenolik dan Flavonoid Total
Ekstrak Metanol Buah dan Daun Patikala
(Etlingera elatior (Jack) R.M.SM),
Pharmaceutical Sciences and Research, 2015;
2 (1), 1–10.
Apak R., Güçlü K., Demirata B., Özyürek M., Çelik
S.E., Bekta?o?lu B., Berker K.I. and Özyurt
D., Comparative evaluation of various total
antioxidant capacity assays applied to phenolic
compounds with the CUPRAC assay,
Molecules, 2007; 12 (7); 1496–1547.
Aziz M.A., Qualitative phytochemical screening
and evaluation of anti-inflammatory, analgesic
and antipyretic activities of Microcos
paniculata barks and fruits, Journal of
Integrative Medicine, 2015; 13 (3); 173–184.
dari: http://dx.doi.org/10.1016/S2095-
4964(15)60179-0.
Bogoriani N.W., Suaniti N.M., Putra A.A.B. and
Lestari K.D.P., The Activity of Cordyline
Terminalis’s Leaf Extract as Antidiabetic in
Obese Wistar Rats, International Journal of
Pharmaceutical Research & Allied Sciences,
2019; 8 (2), 206–213.
Degu A., Engidawork E. and Shibeshi W.,
Evaluation of the anti-diarrheal activity of the
leaf extract of Croton macrostachyus Hocsht.
ex Del. (Euphorbiaceae) in mice model, BMC
Complementary and Alternative Medicine,
2016; 16 (1), 1–11. dari:
http://dx.doi.org/10.1186/s12906-016-1357-9.
Fouedjou R.T., Nguelefack-mbuyo E.P. and Ponou
B.K., Antioxidant Activities and Chemical
Constituents of Extracts from Cordyline
fruticosa ( L .) A . Chev . ( Agavaceae ) and
Eriobotrya japonica ( Thunb ) Lindl , (
Rosaceae ), 2016
Hoelz L.V.B., Horta B.A.C., Araujo J.Q.,
Albuquerque M.G., Alencastro R.B. de and
Silva J.F.M. da, Quantitative structure-activity
relationships of antioxidant phenolic
compounds., Journal of Chemical and
Pharmaceutical Research, 2016; 291–306.
dari:https://www.cabdirect.org/cabdirect/abstra
ct/20113030281 [Diakses pada December 21,
2020].
Lim T.K., Edible Medicinal and Non Medicinal
Plants, Edible Medicinal and Non Medicinal
Plants, 2015; 9, 627–632.
Naher S., Aziz M.A., Akter M.I., Rahman S.M.
Mushiur and Sajon S.R., Analgesic, antiinflammatory
and anti-pyretic activities of
methanolic extract of Cordyline fruticosa (L.)
A. Chev. Leaves, Journal of Research in
Pharmacy, 2019; 23 (2), 198–207.
Naher S., Akter M.I., Rahman S.M.M., Sajon S.R.
and Aziz M.A., Analgesic, anti-inflammatory
and anti-pyretic activities of methanolic extract
of Cordyline fruticosa (L.) A. Chev. Leaves,
Journal of Research in Pharmacy, 2019; 23 (2), 198–207.
Naher S., Aziz M.A., Akter M.I., Rahman S. M.
Mushiur, Sajon S.R. and Mazumder K., Antidiarrheal
activity and brine shrimp lethality
bioassay of methanolic extract of Cordyline
fruticosa ( L .) A . Chev . leaves, Clinical
Phytoscience, 2019a; 5 (15), 4–9.
Naher S., Aziz M.A., Akter M.I., Rahman S. M.
Mushiur, Sajon S.R. and Mazumder K., Antidiarrheal
activity and brine shrimp lethality
bioassay of methanolic extract of Cordyline
fruticosa (L.) A. Chev. leaves, Clinical
Phytoscience, 2019b; 5 (1), 4–9.
Nofianti T., Constantia, Nuraini D., P D.G., P K.Y.
and Suseno A., Aktivitas Hemostatik Ekstrak
Etanol Daun Andong (Cordyline fruticosa [L.]
A.Cheval) terhadap Mencit Jantan Galur
Swiss-Webster, Jurnal Kesehatan Bakti Tunas
Husada, 2016; 16, 118–125.
Nurhayati P., Humairoh D. and Fitri I., Aktivitas
Antibakteri Ekstrak Etanol 96% Daun Andong
Merah (Cordyline Fruticosa (L.) A. Chevas)
terhadap Bakteri Klebsiella Sp, Prosiding
Seminar Nasional Sains Teknologi dan
Analisis, 2018; 136–141.
Panthong A., Kanjanapothi D., Taesotikul T.,
Phankummoon A., Panthong K. and Reutrakul
V., Anti-inflammatory activity of methanolic
extracts from Ventilago harmandiana Pierre,
Journal of Ethnopharmacology, 2004; 91 (2–
3), 237–242.
Prihambodo T.R., Nahrowi and Jayanegara A.,
Antibacterial Activity and Phytochemical
Content of Silage Juice from Tropical Herbal
Leaves, IOP Conference Series: Materials
Science and Engineering, 2019; 546 (4)
Rahman K., Chowdhury A.U., Islam M.T.,
Chowdhury A., Uddin M.E. and Sumi C.D.,
Evaluation of Antidiarrheal Activity of
Methanolic Extract of Maranta arundinacea
Linn . Leaves, 2015; 6.
Reddy C.B., Noor A., Sarada N.C. and
Vijayalakshmi M.A., Antioxidant properties of
Cordyline terminalis (L.) Kunth and Myristica
fragrans Houtt. encapsulated separately into
casein beads, Current Science, 2011; 101 (3),
416–420.
Rupeshkumar M., Kavitha K. and Haldar P.K.,
2014, Role of herbal plants in the diabetes
mellitus therapy: An overview, International
Journal of Applied Pharmaceutics, 6 (3), 1–3.
Saifudin A., Senyawa Alam Metabolit Sekunder
Teori, Konsep, dan Teknik Pemurnian,
Deepublish, Yogyakarta;2014.
Sairam K., Hemalatha S., Kumar A., Srinivasan T.,
Ganesh J., Shankar M. and Venkataraman S.,
Evaluation of anti-diarrhoeal activity in seed
extracts of Mangifera indica, Journal of
Ethnopharmacology, 2003; 84 (1), 11–15.
Sentosa F.T.J., Widiyantoro A. and Jayuska A.,
Senyawa Fenolik dari Fraksi Metanol Batang
Tanaman Andong ( Cordyline Fruticosa ) dan
Aktivitas Sitotoksiknya terhadap Sel HeLa,
Jurnal Kimia Khatulistiwa, 2017; 6 (4), 60–64.
Towiyah, Widiyantoro A. and Destiarti L.,
Karakterisasi Flavonoid dari Fraksi Etil Asetat
Daun Tanaman Andong (Cordyline fruticosa)
dan Aktivitasnya terhadap Plasmodium
falciparum, Jurnal Kimia Khatulistiwa, 2018;
7 (3), 34–39.
Weerapreeyakul N., Nonpunya A., Barusrux S.,
Thitimetharoch T. and Sripanidkulchai
B.,Evaluation of the anticancer potential of six
herbs against a hepatoma cell line, Chinese
Medicine (United Kingdom), 201; 7, 1–7.
Yuslianti E.R., 2018, Pengantar Radikal Bebas dan
Antioksidan, Deepublish, Yogyakarta. 2018;
dari:
https://books.google.co.id/books?hl=id&lr=&i
d=QRxmDwAAQBAJ&oi=fnd&pg=PT12&ot
s=OdYJV5Ylb3&sig=iz5qbsogpz1u1AeWEn6
V1hoV5P4&redir_esc=y#v=onepage&q&f=fal
se [Diakses pada December 21, 2020].
and Andersen Ø.M., Anthocyanin Profile and
Antioxidant Property of Anti-asthma Flowers
of Cordyline terminalis (L.) Kunth
(Agavaceae), Natural Product
Communications; 2020; 15 (5), 1–7.
Ahmad A.R., Juwita J. and Ratulangi S.A.D., 2015,
Penetapan Kadar Fenolik dan Flavonoid Total
Ekstrak Metanol Buah dan Daun Patikala
(Etlingera elatior (Jack) R.M.SM),
Pharmaceutical Sciences and Research, 2015;
2 (1), 1–10.
Apak R., Güçlü K., Demirata B., Özyürek M., Çelik
S.E., Bekta?o?lu B., Berker K.I. and Özyurt
D., Comparative evaluation of various total
antioxidant capacity assays applied to phenolic
compounds with the CUPRAC assay,
Molecules, 2007; 12 (7); 1496–1547.
Aziz M.A., Qualitative phytochemical screening
and evaluation of anti-inflammatory, analgesic
and antipyretic activities of Microcos
paniculata barks and fruits, Journal of
Integrative Medicine, 2015; 13 (3); 173–184.
dari: http://dx.doi.org/10.1016/S2095-
4964(15)60179-0.
Bogoriani N.W., Suaniti N.M., Putra A.A.B. and
Lestari K.D.P., The Activity of Cordyline
Terminalis’s Leaf Extract as Antidiabetic in
Obese Wistar Rats, International Journal of
Pharmaceutical Research & Allied Sciences,
2019; 8 (2), 206–213.
Degu A., Engidawork E. and Shibeshi W.,
Evaluation of the anti-diarrheal activity of the
leaf extract of Croton macrostachyus Hocsht.
ex Del. (Euphorbiaceae) in mice model, BMC
Complementary and Alternative Medicine,
2016; 16 (1), 1–11. dari:
http://dx.doi.org/10.1186/s12906-016-1357-9.
Fouedjou R.T., Nguelefack-mbuyo E.P. and Ponou
B.K., Antioxidant Activities and Chemical
Constituents of Extracts from Cordyline
fruticosa ( L .) A . Chev . ( Agavaceae ) and
Eriobotrya japonica ( Thunb ) Lindl , (
Rosaceae ), 2016
Hoelz L.V.B., Horta B.A.C., Araujo J.Q.,
Albuquerque M.G., Alencastro R.B. de and
Silva J.F.M. da, Quantitative structure-activity
relationships of antioxidant phenolic
compounds., Journal of Chemical and
Pharmaceutical Research, 2016; 291–306.
dari:https://www.cabdirect.org/cabdirect/abstra
ct/20113030281 [Diakses pada December 21,
2020].
Lim T.K., Edible Medicinal and Non Medicinal
Plants, Edible Medicinal and Non Medicinal
Plants, 2015; 9, 627–632.
Naher S., Aziz M.A., Akter M.I., Rahman S.M.
Mushiur and Sajon S.R., Analgesic, antiinflammatory
and anti-pyretic activities of
methanolic extract of Cordyline fruticosa (L.)
A. Chev. Leaves, Journal of Research in
Pharmacy, 2019; 23 (2), 198–207.
Naher S., Akter M.I., Rahman S.M.M., Sajon S.R.
and Aziz M.A., Analgesic, anti-inflammatory
and anti-pyretic activities of methanolic extract
of Cordyline fruticosa (L.) A. Chev. Leaves,
Journal of Research in Pharmacy, 2019; 23 (2), 198–207.
Naher S., Aziz M.A., Akter M.I., Rahman S. M.
Mushiur, Sajon S.R. and Mazumder K., Antidiarrheal
activity and brine shrimp lethality
bioassay of methanolic extract of Cordyline
fruticosa ( L .) A . Chev . leaves, Clinical
Phytoscience, 2019a; 5 (15), 4–9.
Naher S., Aziz M.A., Akter M.I., Rahman S. M.
Mushiur, Sajon S.R. and Mazumder K., Antidiarrheal
activity and brine shrimp lethality
bioassay of methanolic extract of Cordyline
fruticosa (L.) A. Chev. leaves, Clinical
Phytoscience, 2019b; 5 (1), 4–9.
Nofianti T., Constantia, Nuraini D., P D.G., P K.Y.
and Suseno A., Aktivitas Hemostatik Ekstrak
Etanol Daun Andong (Cordyline fruticosa [L.]
A.Cheval) terhadap Mencit Jantan Galur
Swiss-Webster, Jurnal Kesehatan Bakti Tunas
Husada, 2016; 16, 118–125.
Nurhayati P., Humairoh D. and Fitri I., Aktivitas
Antibakteri Ekstrak Etanol 96% Daun Andong
Merah (Cordyline Fruticosa (L.) A. Chevas)
terhadap Bakteri Klebsiella Sp, Prosiding
Seminar Nasional Sains Teknologi dan
Analisis, 2018; 136–141.
Panthong A., Kanjanapothi D., Taesotikul T.,
Phankummoon A., Panthong K. and Reutrakul
V., Anti-inflammatory activity of methanolic
extracts from Ventilago harmandiana Pierre,
Journal of Ethnopharmacology, 2004; 91 (2–
3), 237–242.
Prihambodo T.R., Nahrowi and Jayanegara A.,
Antibacterial Activity and Phytochemical
Content of Silage Juice from Tropical Herbal
Leaves, IOP Conference Series: Materials
Science and Engineering, 2019; 546 (4)
Rahman K., Chowdhury A.U., Islam M.T.,
Chowdhury A., Uddin M.E. and Sumi C.D.,
Evaluation of Antidiarrheal Activity of
Methanolic Extract of Maranta arundinacea
Linn . Leaves, 2015; 6.
Reddy C.B., Noor A., Sarada N.C. and
Vijayalakshmi M.A., Antioxidant properties of
Cordyline terminalis (L.) Kunth and Myristica
fragrans Houtt. encapsulated separately into
casein beads, Current Science, 2011; 101 (3),
416–420.
Rupeshkumar M., Kavitha K. and Haldar P.K.,
2014, Role of herbal plants in the diabetes
mellitus therapy: An overview, International
Journal of Applied Pharmaceutics, 6 (3), 1–3.
Saifudin A., Senyawa Alam Metabolit Sekunder
Teori, Konsep, dan Teknik Pemurnian,
Deepublish, Yogyakarta;2014.
Sairam K., Hemalatha S., Kumar A., Srinivasan T.,
Ganesh J., Shankar M. and Venkataraman S.,
Evaluation of anti-diarrhoeal activity in seed
extracts of Mangifera indica, Journal of
Ethnopharmacology, 2003; 84 (1), 11–15.
Sentosa F.T.J., Widiyantoro A. and Jayuska A.,
Senyawa Fenolik dari Fraksi Metanol Batang
Tanaman Andong ( Cordyline Fruticosa ) dan
Aktivitas Sitotoksiknya terhadap Sel HeLa,
Jurnal Kimia Khatulistiwa, 2017; 6 (4), 60–64.
Towiyah, Widiyantoro A. and Destiarti L.,
Karakterisasi Flavonoid dari Fraksi Etil Asetat
Daun Tanaman Andong (Cordyline fruticosa)
dan Aktivitasnya terhadap Plasmodium
falciparum, Jurnal Kimia Khatulistiwa, 2018;
7 (3), 34–39.
Weerapreeyakul N., Nonpunya A., Barusrux S.,
Thitimetharoch T. and Sripanidkulchai
B.,Evaluation of the anticancer potential of six
herbs against a hepatoma cell line, Chinese
Medicine (United Kingdom), 201; 7, 1–7.
Yuslianti E.R., 2018, Pengantar Radikal Bebas dan
Antioksidan, Deepublish, Yogyakarta. 2018;
dari:
https://books.google.co.id/books?hl=id&lr=&i
d=QRxmDwAAQBAJ&oi=fnd&pg=PT12&ot
s=OdYJV5Ylb3&sig=iz5qbsogpz1u1AeWEn6
V1hoV5P4&redir_esc=y#v=onepage&q&f=fal
se [Diakses pada December 21, 2020].
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Published
2021-05-27
How to Cite
Haryoto, H., & Ardiyani, D. S. (2021). AKTIVITAS FARMAKOLOGI DAN KADAR SENYAWA FENOLIK TOTAL DARI TANAMAN ANDONG MERAH (Cordyline fruticosa L. A. Chev.). Prosiding University Research Colloquium, 743–752. Retrieved from https://repository.urecol.org/index.php/proceeding/article/view/1473
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